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Scream Queens Episode 2×01 “Scream Again” Synopsis

The Chanels are Back…and a New Mystery Begins on the Season 2 Premiere of Scream Queens

FOX released the official episode synopsis for the season two premiere episode of Scream Queens 2×01 titled, “Scream Again.” Check out all the details on the upcoming new episode below.

RELATED | The Cast of SCREAM QUEENS Give First Inside Look at Season 2!

SCREAM QUEENS 2×01 AIRS TUESDAY, SEPT. 20  AT 9|8c. on FOX

Jerry O’Connell (“Mistresses”) and Cecily Strong (“Saturday Night Live”) Guest-Star!

Years after the murderous events at Kappa House, Dean Munsch purchases an abandoned hospital under the guise of fixing the healthcare system in America. After recruiting surgeons, Dr. Brock Holt and Dr. Cassidy Cascade, as well as medical student Zayday Williams, the Dean shocks everyone when she enlists the services of the disgraced Chanels to join the ranks at the teaching hospital. Meanwhile, secrets from the hospital’s past begin to reveal themselves and a new killer surfaces in the all-new “Scream Again” season premiere episode of SCREAM QUEENS.

Cast: Emma Roberts as Chanel Oberlin; Jamie Lee Curtis as Dean Cathy Munsch; Lea Michele as Hester; Abigail Breslin as Chanel #5; Billie Lourd as Chanel #3; Keke Palmer as Zayday Williams; John Stamos as Dr. Brock Holt; Taylor Lautner as Dr. Cassidy Cascade; James Earl as Chamberlain Jackson.

Guest Cast: Niecy Nash as Denise Hemphill; Cecily Strong as Catherine Hobart, Jerry O’Connell as Dr. Mike; Laura Bell Bundy as Nurse Thomas; Jeremy Batiste as Bill; Trilby Glover as Jane.

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